As of the last update, we have found no reported interactions between this medicine and specific foods, supplements, or other compounds. It is possible that unknown interactions exist. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects; refer to the Uses and Precautions tabs or to the manufacturers’ package information for details as this is not covered in Nutrient Interactions. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: adrenalin-like drugs (e.g., ephedrine, methylphenidate), certain high blood pressure drugs (e.g., guanethidine, methyldopa, reserpine, beta-blockers such as propranolol), herbal products containing ephedra.
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain additional decongestants that could increase your risk for side effects. Ask your pharmacist about the safe use of those products.
Loratadine is very similar to desloratadine. Do not use medications containing desloratadine while using loratadine.
This medication may interfere with certain laboratory tests (including allergy skin testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.